Stay Informed, Follow Us!
When looking in the mirror, does your grey hair freaks you out because it seemed too early for you to be greying? Or does seeing those greys serve as a reminder of days gone by? Well, we were intimately familiar with both these feelings and we hated them.
Just like you, we tried to see what could be done to fight those greys, unfortunately, we were told that nothing could be done; it was the nature of things… accept it gracefully and move on – either that or get to dyeing those greys.
Well, for us, that answer was just unacceptable – after all, this is the twenty-first century, mankind must have learnt enough about our own biology to be in a position to fight grey hair! So we invested money hiring competent personnel to find us a viable solution and after eleven (11) months of intense research – both experimental and comparative – Grey Defence® was born. This early research work earned us a US Patent, as well as patents pending in 5 other countries.
We then decided to share our baby with the world, so that folks like you have access to an effective tool to fight your grey. Since September 2011, we have helped many like you to fight their grey hair and hope you will be next.
To quiet the skeptics who continued to doubt the power of Grey Defence®, we did an Open Label Study that was submitted to the only North American government regulator that reviews dietary supplements for safety and efficacy – Health Canada. That effort earned us a Canadian market authorization.
Dear customer, please understand that Health Canada is considered to be one of the toughest regulator of dietary supplements. Published data available as of 2010 showed that 40% of all dietary supplements submission were rejected by them. In short, we went to one of the toughest regulator of dietary supplements to be graded and we passed!
If you still have additional questions about Grey Defence® that is not answered above, or from viewing the video to the top right-side of the screen labeled “Grey Defence Overview”, then feel free to checkout our FAQ page. If you’re ready to jump into the fight to banish those greys, then simply click the Buy Now button at the bottom-right of your screen and let’s get started!
Grey Defence® Xtreme 2.0 is the only grey hair pill with regulatory approval.(PDF Link)
Grey Defence® Xtreme 2.0 is an innovative science based product.(PDF Link)
Grey Defence® Xtreme 2.0 is patent protected.(PDF Link)
To understand how Grey Defence® works you must first understand the different reasons why we grey. There are four main reasons for greying, arrange from smallest to largest (based on the numbers of people affected):
(1) nutrient deficiency specifically Vitamin B12 and Folic Acid deficiency,
(2) greying due to illness such as thyroid illness etc.,
(3) genetic malfunction and,
(4) by far the largest category being greying due to aging.
Studies showed that melanogenesis (the process by which our cells produce melanin) is dependent on key nutrient building blocks such as Vitamin B12 and Folic Acid. A significant number of adults over 50 years old are classified as B12 deficient. In a two-year study conducted by the Department of Dermatology at University Hospital in Uppsala, Sweden, researchers discovered that folic acid, vitamin B12 (also called cobalamin) and sun exposure could help encourage re-pigmentation of the skin and hair. One hundred patients with vitiligo – a condition where the skin loses its pigmentation – were treated with folic acid and B12, and told to increase their exposure to the sun. After three to six months, researchers noted that re-pigmentation was evident in 64% of patients, with six patients experiencing total re-pigmentation.
How is this relevant to greying you may ask. Well it turns out that the root symptom of vitiligo was a build-up of hydrogen peroxide in the skin, which is similar to greying due to aging and stress. So while the mechanism is not fully detailed out, we know that deficiency in B12 and Folic acid can contribute to both vitiligo and its cousin – grey hair.
Grey Defence® is high in supplemental doses of both Vitamin B12 and Folic Acid. In fact, we pride ourselves on only including the most bio-available form of B12 – methylcobalamin – in our formula. Yes this B12 is several times more expensive than cyanocobalamin, but we believe the best products start with the best ingredients.
Thyroid illness is known to affect our hair, it can lead to thinning hair as well as premature greying. The thyroid is a butterfly-shaped gland located in the neck. It is the master gland that controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones. It is estimated that there are millions of Americans with thyroid disease and most do not even know it.
Unfortunately, this type of greying is outside our purview since it is an issue of disease. Grey Defence® is a dietary supplement, not a drug, and does not try to address any disease states, as per FDA guidelines.
The genetic malfunction leading to greying is the most complicated of all the greying causes. There is the “WNT signalling” theory, the “B-Raf and C-Raf gene” theory, “melanocyte stemness” theory and many many more. The bottom line for all these genetic malfunctioning theories is that the hair no longer produces viable melanocyte stem cells than can go on to produce melanin. In short, the hair looses its ability to produce color. This kind of greying distinguishes itself from the others in that it usually manifests itself quite early in our lives usual before the age of 30.
Grey Defence®Xtreme does not work for genetic greying, because the hair follicle no longer produces melanin, the pigment that gives hair its color. Without this pigment, your hair will not reacquire its original color, even if all the bleaching has stopped. We are working hard in the lab to come up with another version of Grey Defence® to address genetic greying. If you are interested in being notified once this product is ready, simply click and fill out the “FEEDBACK” form on the left, be sure to select “New Product Notification”.
This is what most people understand to be the cause of greying, you get old, you grey. It’s just part of the circle of life.
Until recently, the exact mechanism surrounding this type of greying was not very well characterized. Scientist has shown in the last several years that this category of greying is caused by the build-up of hydrogen peroxide at the based the hair follicles that then goes on to bleach the hair as it grows, causing grey hair.
First the hydrogen peroxide interferes with the hairs ability to repair itself by impairing the workings of two important protein repairing enzymes Methionine sulfoxide reductase A (MSRA) and Methionine sulfoxide reductase B (MSRB). Ever notice how grey hair seems more brittle and less flexible that none grey hair? This is why. The next thing and the most prominent of course is the bleach mentioned above.
At this point you may be wondering, ok, so how the heck did hydrogen peroxide get into my body? Well, it got there the old fashion way, our body produces it. Let me explain how…
Earlier I mentioned the word enzymes, well enzyme are very very important protein strands that are found in our body. Without enzymes our basic metabolic functions would not be possible, basically without enzymes there is no life. We have literally trillions of enzymes promoting chemical reactions in our bodies every second of every day. Some of these enzymes are referred to as systemic enzymes, that means they are produced in almost every cell of our bodies.
Each time we breath we create what is referred to as a “respiratory burst”. During a respiratory burst the enzyme NADPH oxidase becomes activated and produces a large quantity of superoxides. Superoxides are also known as ‘free radicals”. Respiratory burst is a very important immune process function which serves to degrade internalized particles and bacteria found in phagocytes cells in our body. Now while these superoxides (free radicals) serves the initial roles as disinfectant, left unchecked they can cause serious harm to none phagocyte cells by stealing hydrogen molecules.
To protect themselves from superoxides running amok, our cell produces the systemic enzyme called Superoxide Dismutase (SOD) which neutralizes the superoxides by turning them into hydrogen peroxide. A small amount of this hydrogen peroxide is converted into hypochlorous acid by the systemic enzyme Myeloperoxidase to fight site specific infection. However the vast amount of hydrogen peroxide produced is quickly broken down into water and oxygen by two other systemic enzymes – Catalase and Glutathione Peroxidase.
Now what you must understand is that when we are young and healthy, our bodies produces all these systemic enzymes in sufficient amounts to keep our systems in balanced and our bodies vibrant. Unfortunately, part of the aging process involves the reduction in the production of systemic enzymes causing our bodies to become frail over time. Key to age related greying is the reduction of the key systemic enzymes Catalase and Glutathione Peroxidase. The reduction in these enzymes leads to micromolar quantities of hydrogen peroxide escaping neutralization. These escapees then accumulate at the base of your hair follicle until they reach a critical concentration at which point the greying process starts.
Please note, stress leads to an increase in respiratory burst, and if its long term will actually speeds up this type of greying. This is why our Presidents tend to grey so quickly in front of our very eyes.
It’s important to note, that even though we are greying due to aging, melanogenesis is still taking place in the hair follicle (the hair is still producing color) and if we can stop the bleaching then we would be able to reverse the greying process.
This is where our dietary supplement Grey Defence® comes in. Grey Defence® is a super-premium dietary supplement that reverses grey hair. It accomplishes this by targeting hydrogen peroxide in the blood stream, in cells and at the base of the hair follicle for removal from the body.
You can view Grey Defence® as a janitorial service for the removal of hydrogen peroxide.
Grey Defence® first reduces the concentration of hydrogen peroxide via chelation. You see, Hydrogen peroxide is a tricky little compound. At low concentration, Catalase has no problem breaking it down to water and oxygen, but once it gets to that critical concentration that can cause greying, it becomes an enzyme inhibitor, specifically it attains the ability to deactivate Catalase – preventing the enzyme from working. What Grey Defence® does is it first removes as much hydrogen peroxide as possible via your kidneys to bring it under that critical concentration level, then it throws a whole bunch of Catalase and Glutathione Peroxidase on the remaining hydrogen peroxide to break them down to water and oxygen.
Finally, Grey Defence addresses the issue of nutrient deficiency by supplementing for Vitamin B12 and Folic Acid, key ingredients in the production of melanin.
The video below provides a detailed overview of the science behind Grey Defence®.
Not only is Grey Defence® effective, it’s also quite safe. Over five thousand customers have used Grey Defence® with no report of any serious adverse reactions. This of course should not be surprising since Grey Defence contains mainly GRAS (generally recognized as safe) ingredients.
Grey Defence® is a marvel of formulation expertise but it does have its limitations. First and foremost, while it is a long term solution whose results can last for years, it is not a cure for greying. Eventually your grey will one day return once you stop using Grey Defence®. Also, while Grey Defence® is effective, it does not work for greying due to genetic malfunction or illness. We are still researching solutions for genetics but nothing is currently available.
Grey Defence® employ advance technologies to promote bioavailability and nutrient absorption that is generally not found in dietary supplements. As I said, “serious solution for people serious about reversing their grey”. One of these technologies involve time release acid protection of the enzymes in the Grey Defence formula. Without this technology the enzymes – which are proteins – would be quickly broken down into amino acids to be used by the body for building muscles. Our advanced acid protection technology prevents this from happening, so Grey Defence® is able to pass through the stomach undigested.
Grey Defence® is not cheap, it’s serious solution, involving serious science, for folks serious about reversing their grey!
If you want cheap imitation products that are not effective, just do a quick Google search and you’ll find plenty, just don’t expect them to work. Why? For one thing, their capsules have no protection against stomach acid, as a result there is no conceivable way for these capsules to pass your stomach in tact. Don’t believe me? Watch the video below. Now if by some miracle any of these unprotected capsules survive the 3 hour journey through your stomach, any surviving Catalase that get’s into your bloodstream will be quickly deactivated by the high concentration of hydrogen peroxide since these cheap products have no advanced chelation capabilities to reduce the concentration of hydrogen peroxide, plus they also lack the ability to promote Glutathione Peroxidase production. You might have noticed that I didn’t even compared the amount of Catalase in Grey Defence® to the amount in these products. Why? Simple, it’s irrelevant because none of what is in these unprotected capsules will survive the 3-hour trip through your stomach, but for the curious we have 17 times the amount of Catalase as the strongest of the cheap imitators. As I said, “serious solution”!
So you decide, how serious you about reversing your grey.
Our recent impact survey reviewed the effectiveness of Grey Defence®. The results were quite impressive with a documented 65% effectiveness in reversing grey hair due to aging and stress. We are looking forward to next year’s review.
Grey Defence® works methodically over time to reverse greying due to stress, nutrient deficiency and aging. You need to use Grey Defence® as directed for a minimum of 6 months to determine if it’s right for you – don’t worry the risk is ours (see guarantee below). During this time you should expect to see a 3 -5 percent recoloring, this tells you that Grey Defence® is right for you (please note for those with very few grey hairs, this may not be noticeable and you may need more time). Full reversal may take up to 18 months.
Now for those who may be thinking that reversing you head of grey in 18 months is not fast enough, I would like to ask you this – in comparison to what? After all, 30 minutes ago you were skeptical that this was even possible. Oh well, at least it’s progress. *smile*
VERY IMPORTANT NOTICE:
DO NOT BUY Grey Defence® if you do not intend to use the product for at least 6 months. Also, we strongly discourage those that started greying in their twenties or earlier from purchasing Grey Defence® since it’s most likely that your greying is due to either illness or genetic malfunction.
Greying may be complicated but solving it can be as simple as taking a single capsule per day.
1) There are multiple reasons for greying with the largest being aging.
2) Grey Defence® is an effective treatment with a 65% demonstrated success rate.
3) Grey Defence® is supported by real science.
4) You need to use Grey Defence® for at least 6 months to determine if it’ll work for you.
5) With our 6 month performance guarantee, all the risks is ours!
Frequently Asked Questions
Yes, Grey Defence® works. Grey Defence®contains several essential amino acids, vitamins and enzymes that together form a catalytic force for the metabolic breakdown of hydrogen peroxide found in hair follicles. During aging the build up of hydrogen peroxide is what causes gray hair. The active ingredients in Grey Defence® are found naturally in healthy hair follicles but are either missing, deactivated or in very low concentration in grey hair follicles as compared to normal hair follicles.
Grey Defence® provides a measured dosage to supplement the body’s diminished stores of these hydrogen peroxide oxidative compounds. Grey Defence® is designed to breakdown hydrogen peroxide which bleaches the hair while it grows.
Assuming normal melanogenesis, in the absence of hydrogen peroxide, the hair should return to its natural pigmentation during the next anagen growth cycle.
Unfortunately no. There are numerous reasons why we grey, it could be genetic; it could be a deficiency in certain key compounds such as Vitamin B12 and folic acid; it could be due to normal aging or a stressful lifestyle, it could be due to oxidative stress from a polluted environment that resulted in free radical damage; and of course it could be a combination of all the above.
Grey Defence® is a dietary supplement that was formulated to augment the body’s natural defences against hair canities that are age, oxidative stress and/or nutrient deficiency (Vitamin B12 and folic acid) related. Grey Defence® may not work for those that have a genetic malfunction or illness that is causing their greying (this may change in the future, we are currently working on a genetic targeted solution – stay tune).
Yes, Grey Defence® is safe for human consumption. First we start with high quality, carefully selected ingredients. Second Grey Defence® is manufactured in a FDA/Health Canada approved certified GMP facility. Finally, each batch is carefully tested to make sure that it meets all regulatory safety standards.
Grey Defence® when used as directed can assist the body to slow, stop and reverse the signs of greying; however Grey Defence® is not a cure for greying. Greying should be viewed as a symptom of an underlying condition, not the condition itself. So while Grey Defence® may aid in addressing the symptom, the underlying condition still persist and eventually will re-assert itself, after you stop using Grey Defence® for a period of time.
Unfortunately, as of the time of this writing there were no known cure for greying.
Grey Defence® works methodically over time to reverse greying due to stress, nutrient deficiency and aging. To know if it will work for you, you simply need to use as directed for a minimum of 6 months (don’t worry the risk is ours). During this time you should expect to see a 3 -5 percent recoloring (please note for those with very few grey hairs, this may not be noticeable and you may need more time), this tells you that Grey Defence® is right for you. Full reversal may take up to 18 months.
Please note that Grey Defence® is a dietary supplement not a pharmaceutical drug – its contents are vitamin, amino acids and enzymes. The ingredients are what the body needs on a daily basis to get rid of waste by-product hydrogen peroxide. If Grey Defence® was able to reverse your gray hair then that means either your body was not producing enough of the compounds it required to flush waste by-product hydrogen peroxide from your system or your diet does not supply adequate amounts. In either case you required a supplemental source, so continued use of Grey Defence® is beneficial to overall health, just as much as taking a multivitamin each day is.
Having said that, Grey Defence® does supply a concentrated dose of these ingredients which exceeds what is required for general maintenance. Please note that you can discontinue using Grey Defence® 6 months after your hair color recovers, but that is NOT our recommendation. Our recommendation would be that you reduce, but not totally eliminate Grey Defence® and instead use it just like any other vitamin enriched dietary supplement. You can reduce to “one pill per day” or “per other day” based on you own assessment and needs.
Once the ingredients in Grey Defence® enters your body, they flows along the blood stream seeking out hydrogen peroxide wherever it may lurk. Whenever the ingredients comes into contact with hydrogen peroxide they neutralizes it instantaneously. This means that Grey Defence® will stop gray hair on your head, your face and all over your body.
There are no known or reported drug interactions or side effects from using Grey Defence®. Grey Defence® contains ingredients already found in our bodies. This includes vitamins, amino acids and enzymes. Therefore it should come as no surprise that Grey Defence® is safe. Having said that, if you are currently on doctor prescribed medications, we recommend you consult with your physician before taking Grey Defence®.
Grey Defence® is a proprietary blend of multiple key ingredients that appears below in the ingredients list at the bottom of this page.
Each bottle of Grey Defence® contains 1 month’s supply of product. Grey Defence® is to be taken daily on an empty stomach, preferably first thing in the morning.
No, Grey Defence® cannot re-color existing gray hair. Grey Defence® works by neutralizing waste by-product hydrogen peroxide – one of the chief causes of graying hair. Once the body sheds older gray hair the new growth will be free of hydrogen peroxide damage and bleaching – thereby retaining its natural color. This new naturally colored regrowth is the process by which reversal is realized. This also means Grey Defence® is an effective tool to slow down and stop gray for those at the early stages of graying.
Yes, you can take Grey Defence® with your multivitamin, however please make sure that if your multivitamin contains SELENIUM that the daily dose amount does not exceed 200mcg.
No, Grey Defence® is not similar to the ‘… Away Grey’ (i.e. Get and Go) branded grey hair pills that also contain Catalase. Just containing Catalase is not enough to be effective. These pills are stuck in the technology of 2009, while Grey Defence® regularly upgrades to incorporate the latest scientific breakthroughs. Here are the key ways Grey Defence® is different:
These are the important ways in which Grey Defence® differs from those “… Away Grey” branded grey hair pills. In summary Grey Defence® incorporates cutting edge scientific findings, has more of the key ingredients, utilizes advance acid protection and includes technology that promotes the absorption of the key ingredients from the time they enter your mouth to the moment they find their way into your cells.
No, Grey Defence® only supplements the amount of Catalase in the body by providing an external supply. It does not stimulate the body’s native ability to produce Catalase.
Our focus when developing Grey Defence® was solely to develop the best gray hair treatment solution. However, we did take a whole-health view of our mandate – so yes – besides gray hair reversal there are additional health attributes such as potential longevity effects as well as others. However, as previously mentioned, our focus is to develop the best gray hair treatment available so these secondary health benefits are not on-label-claims and may never be, that however does not mean they do not exist.
The first shipment of Grey Defence® – Grey Defence® Original – took place on September 12, 2011.
The FDA does not review dietary supplements unless they are unsafe or have misleading claims. However, Grey Defence® does satisfy the following statutes:
17. What is the basis of the claims: (a) Supports Immune Health and (b) Helps Reduce Tiredness & Fatigue?
These are 2012, Article 13(1) General Health Claims authorized by EFSA (European Food Safety Authority) – which, therefore meets FDA substantiation requirements. Specifically the claims made on our label are authorized under specific subsections as outlined in the links below. Please note the links will take you to PDF documents that will open in a new window. Make sure your pop-up blockers are off.
(1) Vitamin B6 – Immune Health: 2009;7(9):1225
No adverse effects have been associated with excess B-12 intake from food or supplements in healthy individuals, as a result there is no upper intake limit established. B Vitamins such as B6, Folic Acid and B12 are a water-soluble vitamins. Water-soluble vitamins dissolve in water. After the body uses these vitamins, leftover amounts leave the body through the urine.
Hydrogen peroxide is not produced as a reaction to infection, but rather as a result of “respiratory burst” where the enzyme NADPH oxidase produces large quantities of superoxides (free radicals) as a by-product of normal metabolic activities.
Left un-neutralized, free radicals will damage cells and reduce their lifespan. The body produces Superoxide dismutase another enzyme whose sole purpose is the dismutation of superoxides into oxygen and hydrogen peroxide. In short, each breath leads to the eventual production of hydrogen peroxide, regardless of whether we have an infection or not.
To fight site specific infections an enzyme called Myeloperoxidase converts a small amount of the large quantity of hydrogen peroxide produced with every breath to hypochlorous acid, it is this acid that is used to fight SITE SPECIFIC bacterial infection and there is no shortage of hydrogen peroxide production for whenever this conversion is required.
In addition several studies have shown that hydrogen peroxide deactivates the enzymes Methionine Sulfoxide Reductases A and B (MSRA, MSRB), whose metabolic function is the repair of oxidative damage to proteins to restore biological activity.
Further, the body produces two enzymes to control hydrogen peroxide accumulation (Catalase & Glutathione Peroxidase) as we get older the production of systemic antioxidant enzyme are reduce due to the body’s rationing system – this is essentially what aging is. Grey Defence® simply augments this reduced production while employing additional measures to control the accumulation of hydrogen peroxide.
For many types of oral medications that are not susceptible to stomach acid (e.g. multivitamins), there’s no need for acid protection (enteric coating). However, if any of the key ingredients in a formulation is known to be susceptible to stomach acid, then enteric coating is recommended. On the other hand, if any of the key ingredients are HIGHLY susceptible to stomach acid, such as enzymes – enzymes are proteins and stomach acid is very efficient at breaking down proteins – then without proper stomach acid protection the enzymes are quickly destroyed and broken down to amino acids.
Eating food to block the effects of stomach acid digestion on unprotected pills is a losing proposition since these foods will be broken down as well – after all, breaking down food is why we have stomachs in the first place. Additionally, the more stuff we have in our stomach, the longer the digestive process takes – it can take up to 4 hours to clear your stomach after a meal (the above linked video shows what happens to unprotected pills after just 1 hour).
Beside the fact that eating solid food prolongs the time it takes for your stomach to clear, eating a meal ends up reducing bioavailability of your grey hair pill. This is because these pills contain enzymes – which are macro-molecules – that ends up competing with the macro-molecules from your digested meal for space on the limited number of absorption transports vessels found in your small intestines.
In fact, speed and bioavailability explains why we recommend taking Grey Defence® – the only grey hair pill with acid protection – on an empty stomach. The reason Grey Defence® works so well is due entirely to the fact that we stick to best of breed science.
Regarding costs, we believe in adhering to sound scientific principles, even if that costs more. Our first and primary responsibility to our customers is not to produce a cheap product. Rather, it is to produce a product that works. To do this requires not only cutting edge science, it also requires adherence to sound scientific principles, we deliver on both.
So what are you waiting for? Start grey defencing today!